nswd

You can never hold back spring

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I often have to cut into the brain and it is something I hate doing. With a pair of short-wave diathermy forceps I coagulate a few millimetres of the brain’s surface, turning the living, glittering pia arachnoid – the transparent membrane that covers the brain – along with its minute and elegant blood vessels, into an ugly scab. With a pair of microscopic scissors I then cut the blood vessels and dig downwards with a fine sucker. I look down the operating microscope, feeling my way through the soft white substance of the brain, trying to find the tumour.

{ Henry Marsh/Granta | Continue reading }

photo { Helmut Newton }

Keep going until you stop

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Last fall I had myself tested for 320 chemicals I might have picked up from food, drink, the air I breathe, and the products that touch my skin—my own secret stash of compounds acquired by merely living. It includes older chemicals that I might have been exposed to decades ago, such as DDT and PCBs; pollutants like lead, mercury, and dioxins; newer pesticides and plastic ingredients; and the near-miraculous compounds that lurk just beneath the surface of modern life, making shampoos fragrant, pans nonstick, and fabrics water-resistant and fire-safe.

The tests are too expensive for most individuals—National Geographic paid for mine, which would normally cost around $15,000—and only a few labs have the technical expertise to detect the trace amounts involved. I ran the tests to learn what substances build up in a typical American over a lifetime, and where they might come from. I was also searching for a way to think about risks, benefits, and uncertainty. […]

“In toxicology, dose is everything,” says Karl Rozman, a toxicologist at the University of Kansas Medical Center, “and these doses are too low to be dangerous.” […] Yet even though many health statistics have been improving over the past few decades, a few illnesses are rising mysteriously. From the early 1980s through the late 1990s, autism increased tenfold; from the early 1970s through the mid-1990s, one type of leukemia was up 62 percent, male birth defects doubled, and childhood brain cancer was up 40 percent. Some experts suspect a link to the man-made chemicals that pervade our food, water, and air. There’s little firm evidence. But over the years, one chemical after another that was thought to be harmless turned out otherwise once the facts were in. […]

PCBs, oily liquids or solids, can persist in the environment for decades. In animals, they impair liver function, raise blood lipids, and cause cancers. Some of the 209 different PCBs chemically resemble dioxins and cause other mischief in lab animals: reproductive and nervous system damage, as well as developmental problems. By 1976, the toxicity of PCBs was unmistakable; the United States banned them, and GE stopped using them. But until then, GE legally dumped excess PCBs into the Hudson, which swept them all the way downriver to Poughkeepsie, one of eight cities that draw their drinking water from the Hudson.

In 1984, a 200-mile (300 kilometers) stretch of the Hudson, from Hudson Falls to New York City, was declared a superfund site, and plans to rid the river of PCBs were set in motion. GE has spent 300 million dollars on the cleanup so far. […]

And that faint lavender scent as I shampoo my hair? Credit it to phthalates, molecules that dissolve fragrances, thicken lotions, and add flexibility to PVC, vinyl, and some intravenous tubes in hospitals. The dashboards of most cars are loaded with phthalates, and so is some plastic food wrap. Heat and wear can release phthalate molecules, and humans swallow them or absorb them through the skin. […]

My inventory of household chemicals also includes perfluorinated acids (PFAs)—tough, chemically resistant compounds that go into making nonstick and stain-resistant coatings. 3M also used them in its Scotchgard protector products until it found that the specific PFA compounds in Scotchgard were escaping into the environment and phased them out. In animals these chemicals damage the liver, affect thyroid hormones, and cause birth defects and perhaps cancer, but not much is known about their toxicity in humans. […]

And then there is mercury, a neurotoxin that can permanently impair memory, learning centers, and behavior. Coal-burning power plants are a major source of mercury, sending it out their stacks into the atmosphere, where it disperses in the wind, falls in rain, and eventually washes into lakes, streams, or oceans. There bacteria transform it into a compound called methylmercury, which moves up the food chain after plankton absorb it from the water and are eaten by small fish. Large predatory fish at the top of the marine food chain, like tuna and swordfish, accumulate the highest concentrations of methylmercury—and pass it on to seafood lovers.

I don’t eat much fish, and the levels of mercury in my blood were modest. But I wondered what would happen if I gorged on large fish for a meal or two. So one afternoon I bought some halibut and swordfish at a fish market in the old Ferry Building on San Francisco Bay. Both were caught in the ocean just outside the Golden Gate, where they might have picked up mercury from the old mines. That night I ate the halibut with basil and a dash of soy sauce; I downed the swordfish for breakfast with eggs (cooked in my nonstick pan).

Twenty-four hours later I had my blood drawn and retested. My level of mercury had more than doubled, from 5 micrograms per liter to a higher-than-recommended 12. Mercury at 70 or 80 micrograms per liter is dangerous for adults, says Leo Trasande, and much lower levels can affect children. “Children have suffered losses in IQ at 5.8 micrograms.” He advises me to avoid repeating the gorge experiment.

{ National Geographic | Continue reading | Thanks Tim }

related { Stanford University researchers concluded that fruits, vegetables and meat labeled organic were, on average, no more nutritious than their conventional counterparts. | NYT }

He gazes ahead reading on the wall a scrawled chalk legend Wet Dream and a phallic design

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As noted in a previous posting, a number of studies have found that males outperform females on tests of general knowledge. The reasons for this are not yet clear. Women’s poorer test performance could be because they actually have acquired less knowledge than men, or it could be that they are not accessing all the knowledge they have. […]

Sex differences in general knowledge favouring males that were identified in a number of studies have been attributed to differing interests between men and women rather than differences in ability.

Another possibility that has not been explored in the research literature is that stereotype threat could have a detrimental effect on the performance of females in tests. […] For example, women who are reminded of their female identity perform more poorly on maths tests compared to a control group.

{ Eye on Psych | Continue reading }

The way that the visual centers of men and women’s brains works is different, finds new research published in BioMed Central’s open access journal Biology of Sex Differences. Men have greater sensitivity to fine detail and rapidly moving stimuli, but women are better at discriminating between colors.

{ EurekAlert | Continue reading }

‘The price of creation is never too high. The price of living with other people always is.’ –Charles Bukowski

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Languages are continually changing, not just words but also grammar. A recent study examines how such changes happen. […]

Historical linguists, who document and study language change, have long noticed that language changes have a sneaky quality, starting small and unobtrusive and then gradually conquering more ground, a process termed ‘actualization’. […]

Consider the development of so-called downtoners – grammatical elements that minimize the force of the word they accompany. Nineteenth-century English saw the emergence of a new downtoner, all but, meaning ‘almost’. All but started out being used only with adjectives, as in her escape was all but miraculous. But later it also began to turn up with verbs, as in until his clothes all but dropped from him. In grammatical terms, that is a fairly big leap, but when looked at closely the leap is found to go in smaller steps. Before all but spread to verbs, it appeared with past participles, which very much resemble both adjectives and verbs, as in her breath was all but gone.

{ Linguistic Society of America }

Burn so bright I’m gonna make you blind

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{ Weapon system patented by Aleksandr Georgievich Semenov. Soldiers inside an armoured tank, under battle conditions, can dispose of their biological waste products in an unwasteful way: encasing those materials, together with explosives, in artillery shells that they then fire at the enemy. | full story }

‘So are you sitting next to President Obama or may I join you?’ –Steven Amiri

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Nowhere in the United States do you have the right to credibly contract for a lifetime marital partnership.

Every state currently allows some form of “no fault” divorce - divorce not based on any wrongdoing of a party, but simply because the parties claim they don’t want to be married anymore. Even though the couple may “vow” to remain together until one of them dies, everyone knows these vows have no legal or real-world effect. The marital “contract” is not a contract at all.

Imagine a regular legal contract in which either party could end the agreement by saying he didn’t like it anymore. […]

Marriage once did have a legal effect - once married, parties could not divorce without a really good reason (physical cruelty, desertion, or adultery). Not coincidentally, marriages were much more likely to be reliable lifetime partnerships.

{ The View from Hell | Continue reading }

photo { Sam Haskins }

What’s up with your bad breath onion rings

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When Wallace Craig dissected the feeding behavior of doves, his experimental animal of choice, he discovered the existence of two distinct phases - an appetitive and a consummatory phase. He defined appetite as “a state of agitation”, which continues until food is presented, whereupon phase 2 begins. That’s the phase you and I call eating. It’s followed by a third phase of relative rest, which Craig called the state of satisfaction. You are forgiven if you now ask “what science nugget could possibly be hidden in this platitude.” But the best-hidden gems are often those, which are in plain sight. […]

When Craig published his paper in 1917 he described the behaviors of his doves as instinctive. In other words, being driven by some innate processes which require no conscious decision making nor any degree of intellect. Today we know a lot more about those “innate processes”, particularly that they are the result of a complex conversation between neurons and hormones playing out in the recesses of the animal brain. Not only do we know the chains of command running from brain centre to periphery we also know the hormones (at least some of them) by names, such as Neuropeptide Y (NPY) or Leptin. You don’t need to remember them. What you need to remember is that “instinctive” has matured from a black box stage to the stage of neurohormonal mechanisms, which can be tested quantitatively in the lab with experimental animals. […]

NPY is the most potent “orexigenic” peptide currently known. That’s science speak for appetite stimulating peptide. Now you also know what it means when I tell you that leptin’s effect is just the opposite, that is, anorexigenic, or appetite suppressant. Inject NPY into the right places of a rat’s brain and it will turn into a voracious eater. Give obese rats leptin, and they slim down.

{ Chronic Health | Continue reading }

At four, she said. Time ever passing.

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{ When Tarzan leaps from a swinging rope, when should he let go to jump furthest? The answer isn’t as simple as you might think. }

Oowah oowah is my disco call

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At 12 or 13, we started taking buses to New York City and going to raves. My friends and I discovered this underground culture and adopted this great style that was still foreign to our small upstate community. At the height of the rave scene, I could have described myself as a “polo” raver. I’d wear 60-inch wide jeans called Aura’s E, which was a brand by this girl in Long Island named Aura. I shaved my eyebrows completely off, pierced everything on my face, put platforms on my running sneakers… I’d work day and night in the mall upstate so that I could buy my rave tickets and take bus trips to get all the cool clothes in the city. I found out about everything from shops like Liquid Sky and Satellite Records––they would put flyers out and you had to call hotlines to find out all the rave info. All the great mixtapes were sold at the stores too. It was a real beautiful time to be a teenager and so close to NYC.

{ David Benjamin Sherry | Continue reading }

Mondo Macabro

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The death of an autoerotic asphyxiation fan ended up providing science with some valuable observations of what happens during choking.

On Twitter recently, I’ve been highlighting some really bad ideas courtesy of the medical literature. From injecting vaseline into your own penis, to pumping compressed air up your rectum for a joke, people have tried it and they’ve ended up on PubMed as a result.

{ Neuroskeptic | Continue reading }

And imagine such an enormous mass of countless particles of sand multiplied as often as there are leaves in the forest, drops of water in the mighty ocean, feathers on birds, scales on fish, hairs on animals, atoms in the vast expanse of the air

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The sorites paradox is a paradox that arises from vague predicates.

The paradox of the heap is an example of this paradox which arises when one considers a heap of sand, from which grains are individually removed. Is it still a heap when only one grain remains? If not, when did it change from a heap to a non-heap?

{ Wikipedia | Continue reading }

quote { James Joyce, A Portrait Of The Artist As A Young Man, 1916 }

photo { Roger Minick, Couple at Mittens Overlook, 1980 }

It’s the life in your years, not the years in your life

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A low-calorie diet boosts health but does not prolong life, at least not in rhesus monkeys, scientists found in a new study into a long-held link between food restriction and longevity.

Spanning 23 years, the research found monkeys that ate fewer calories than non-dieting counterparts were healthier but did not live any longer.

Rhesus monkeys (Macaca mulatta) are a preferred choice for lab study, as they are long-lived primates like humans – their average lifespan in captivity is 27 years and the usual maximum is 40 years.

The exceptionally long study, launched at the U.S. National Institute on Ageing (NIA) in Maryland in 1987, saw monkeys of different ages fed a diet 30% lower in calories than others that followed a ‘normal’, nutritious diet.

{ Cosmos | Continue reading }

photo { Krass Clement }

He had learned of the existence of a number computed to a relative degree of accuracy to be of such magnitude and of so many places, e.g., the 9th power of the 9th power of 9

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Blackjack players who “count cards” keep track of cards that have already been played and use this knowledge to turn the probability of winning in their favor. Though casinos try to eject card counters or otherwise make their task more difficult, card counting is perfectly legal. So long as card counters rely on their own memory and computational skills, they have violated no laws and can make sizable profits. By contrast, if players use a “device” to help them count cards, like a calculator or smartphone, they have committed a serious crime.

I consider two potential justifications for anti-device legislation and find both lacking. The first is that, unlike natural card counting, device-assisted card counting requires cognitive enhancement. It makes card counting less natural and is unfair to casinos and should therefore be prohibited. The second potential justification relies on the privacy of our thoughts. On this view, natural card counting is a kind of cheating that warrants punishment. We do not criminalize natural card counting, however, because such laws would interfere with our thought privacy.

{ Adam J. Kolber /SSRN | Continue reading }

Club style, rich wine-colored leather, gloss renewable with a minimum of labour by use of linseed oil and vinegar

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The first goal was to halve the proportion of the world’s population living on a dollar a day by 2015. […]

The target had actually been met in 2008, seven years ahead of schedule. This staggering achievement received no fanfare, perhaps because the miracle had not been created by Western governments but by the economic progress of China and India.

{ Telegraph | Continue reading }

photo { Christophe Agou }

‘Happiness is not an ideal of reason but of imagination.’ –Kant

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{ Depressed Copywriter }

Unseen, one summer eve, you kissed me in four places. And with loving pencil you shaded my eyes, my bosom and my shame.

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{ Study finds gene that predicts happiness in women }

The eyes in which a tear and a smile strove ever for the mastery were of the dimensions of a cauliflower

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Emotion recognition, a core component of emotional intelligence, is the general ability to recognize emotions. […]

For decades, researchers have known that skill in emotion recognition predicts positive outcomes in a wide range of contexts. From business executives to foreign service officers to elementary school principals, studies have shown a positive association between skill in emotion recognition and success in a wide variety of educational, workplace, or organizational contexts. Sensitivity to the internal states of colleagues, note the authors, can assist in coordinating activities and working independently. Emotion recognition, however, is a complex skill.

A person can express emotion by voice tones, facial expressions, body movements, or a combination of these “channels.” Each channel or combination can communicate a number of different emotions. […] Our facial expressions are, according to published research, highly controllable, express the information we choose to communicate, and as a result, “this information is more subject to impression management.” Emotion information conveyed through body movement or voice channels, however, may provide, according to the authors, a truer window into a person’s feelings. The ability to control the expression of emotion through these channels is more difficult, and requires more effort. […]

Emotion recognition is about reading social cues. The researchers label this skill “nonverbal eavesdropping.” […] Some people have problems when they lack the ability to read social cues around them. The study authors noted that some people have a different kind of problem with emotion recognition: They have the potential to “read too much” in a particular situation. […]

Sadness was the easiest emotion to recognize and fear the most difficult;

Accuracy did not differ across positive versus negative emotions;

Accuracy varied by channel, with emotions easier to recognize through facial photographs than vocal tone;

Anger and fear were more easier to recognize in the voice;

Happiness and sadness were relatively easier to recognize in the face;

Emotional eavesdropping ability varied significantly across emotions, with anger and fear were more easily eavesdropped than happiness or sadness;

{ Psycholawgy | Continue reading }

artwork { Pablo Picasso, Femme étendue lisant, 1952 }

There can be no doubt that all our knowledge begins with experience

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Phenomenology is a philosophical method for uncovering the structure of lived experience by describing what it is like from a first person perspective. Rather than attempting to prove a set of objective facts, phenomenology tracks the way that a meaningful experience of the world emerges for someone in the total situation of their Being-in-the-world. It’s not that facts are unimportant, but rather that they are not meaningful in themselves; they become meaningful when they are experienced by someone in relation to a wider context or horizon.

What happens when that horizon shrinks to the space of a 6-by-9 cell?

{ NY Times | Continue reading }

Something lives only as long as the last person who remembers it

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What are the most important examples of lost or forgotten knowledge?

For example, as Matt Ridley states in The Rational Optimist, “nobody really knows how to use an Acheulean hand axe, and until recently nobody knew how to build a medieval siege catapult known as a trebuchet.”

{ Quora | Continue reading }

The entropy formula for the Ricci flow and its geometric applications

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Grigori Perelman is one of the greatest mathematicians of our time, a Russian genius who solved the Poincaré Conjecture, which plagued the brightest minds for a century. At the height of his fame, he refused a million-dollar award for his work. Then he disappeared. Our writer hunts him down on the streets of St. Petersburg. […]

Word was that someone had solved an unsolvable math problem. The Poincaré conjecture concerns three-dimensional spheres, and it has broad implications for spatial relations and quantum physics, even helping to explain the shape of the universe. For nearly 100 years the conjecture had confused the sharpest minds in math, many of whom claimed to have proven it, only to have their work discarded upon scrutiny. The problem had broken spirits, wasted lives. By the time Perelman defeated the conjecture, after many years of concentrated exertion, the Poincaré had affected him so profoundly that he appeared broken too.

Perelman, now 46, had a certain flair. When he completed his proof, over a number of months in 2002 and 2003, he did not publish his findings in a peer-reviewed journal, as protocol would suggest. Nor did he vet his conclusions with the mathematicians he knew in Russia, Europe and the U.S. He simply posted his solution online in three parts—the first was named “The Entropy Formula for the Ricci Flow and Its Geometric Applications”—and then e-mailed an abstract to several former associates, many of whom he had not contacted in nearly a decade.

{ Brett Forrest | Continue reading }



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