What events might nullify these calculations?

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Networks of muscles, of brain cells, of airways and lungs, of heart and vessels operate largely independently. Every couple of hours, though, in as little as 30 seconds, the barriers break down. Suddenly, there’s synchrony. All the disjointed activity of deep sleep starts to connect with its surroundings. Each network joins the larger team. This change, marking the transition from deep to light sleep, has only recently been understood in detail. […]

Similar syncing happens all the time in everyday life. Systems of all sorts constantly connect. Bus stops pop up near train stations, allowing commuters to hop from one transit network to another. New friends join your social circle, linking your network of friends to theirs. Telephones, banks, power plants all come online — and connect online.

A rich area of research has long been devoted to understanding how players — whether bodily organs, people, bus stops, companies or countries — connect and interact to create webs called networks. An advance in the late 1990s led to a boom in network science, enabling sophisticated analyses of how networks function and sometimes fail. But more recently investigators have awakened to the idea that it’s not enough to know how isolated networks work; studying how networks interact with one another is just as important. Today, the frontier field is not network science, but the science of networks of networks. […]

Findings so far suggest that networks of networks pose risks of catastrophic danger that can exceed the risks in isolated systems. A seemingly benign disruption can generate rippling negative effects. Those effects can cost millions of dollars, or even billions, when stock markets crash, half of India loses power or an Icelandic volcano spews ash into the sky, shutting down air travel and overwhelming hotels and rental car companies. In other cases, failure within a network of networks can mean the difference between a minor disease outbreak or a pandemic, a foiled terrorist attack or one that kills thousands of people.

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