‘How now? a rat? Dead, for a ducat, dead!’ –Shakespeare

29.jpg

The life cycle of the parasite Toxoplasma gondii goes like this: Toxoplasma reproduces inside the intestine of a cat, which sheds the parasite in its feces. Rats then ingest the parasite when they consume food or water contaminated with cat feces. The parasite takes up residence in the rat’s brain and, once the rat gets eaten by a cat, it starts the cycle all over again.

Researchers have known for a few years that a rat infected with Toxoplasma loses its natural response to cat urine and no longer fears the smell. And they know that the parasite settles in the rat’s amygdala, the part of the brain that processes fear and emotions. Now a new study in the journal PLoS ONE adds another bizarre piece to the tale: When male rats infected with Toxoplasma smell cat urine, they have altered activity in the fear part of the brain as well as increased activity in the part of the brain that is responsible for sexual behavior and normally activates after exposure to a female rat.

The double messages of “you smell a cat but he’s not dangerous” and “that cat is a potential mate” lure the rat into the kitty’s deadly territory, just what the parasite needs to reproduce.

{ Smithsonia magazine | Continue reading }