Every day, the same, again

55.jpgrats, with holes in their knee joints drilled by the researchers to mimic cancer pain, who where exposed to Mozart K448 Sonata, consumed more food, gained more weight, and expressed lower amounts of p38a and p38b than the control group.

Many people may not have noticed yet but a few months ago, a kind of unassuming little pickup truck emoji appeared on most peoples’ electronic devices. The story behind that little truck is actually a window into the shadowy corporate cabal behind emoji and the big and sometimes dare we say DARK MONEY that companies are pushing around behind the scenes to shape our keyboards and influence how we communicate every day. [NPR]

What Is Rough Sex, Who Does It, and Who Likes It?

What makes a good question? What principles govern human information acquisition and how do people decide which query to conduct to achieve their goals?

This study uses the unprecedented changes in the sex ratio due to the losses of men during World War II to identify the impacts of the gender imbalance on marriage market and birth outcomes in Japan.

Bitcoin uses more electricity than Argentina

Jamaica faces marijuana shortage as farmers struggle and Louis Vuitton pulls “Jamaican Sweater” from online store after using wrong flag colors

Food sharing has become quite popular over the last decade, with companies offering food options specifically designed to be shared. As the popularity has grown, so too has concerns over the potential negative impact on consumer health. Despite companies’ explicit claims to the contrary, critics maintain that food sharing may be encouraging excessive caloric intake. The current article provides the first systematic exploration of why this may be happening. […] Our findings suggest that food sharing may be encouraging excessive caloric intake by leading consumers to underestimate the fattening potential brought on by shared food consumption.

We argue that Internet search reduces the likelihood of information being stored in memory.

Scientists are working on a shot that could protect against Covid-19, its variants, certain seasonal colds — and the next coronavirus pandemic. [NY Times]

In evolutionary terms, SARS-CoV-2 is an ‘evasion-light’ pathogen. It has not had to acquire an armamentarium of molecular features to outwit immune responses in general and neutralizing antibodies in particular. This is because it currently transmits from one person to another before immune responses have developed — and, in many cases, before disease symptoms are noted. Other pathogens are ‘evasion-strong’. The extreme example is HIV. It frequently co-exists with human immune systems, possibly for years, before onward transmission. […] The emergence of another pathogen with the evasion capabilities of HIV might be the worse-case scenario for a pandemic. […] A special class of protective antibodies called broadly neutralizing antibodies acts against many different strains of related virus — for example, of HIV, influenza or coronavirus. Such antibodies could be used as first-line drugs to prevent or treat viruses in a given family, including new lineages or strains that have not yet emerged. More importantly, they could be used to design vaccines against many members of a given family of viruses. [ Nature]

Israel’s swift vaccination rollout has made it the largest real-world study of Pfizer Inc’s COVID-19 vaccine. Results are trickling in. […] Among the first fully-vaccinated group there was a 53% reduction in new cases, a 39% decline in hospitalizations and a 31% drop in severe illnesses from mid-January until Feb. 6, said Eran Segal, data scientist at the Weizmann Institute of Science in Rehovot, Israel. In the same period, among people under age 60 who became eligible for shots later, new cases dropped 20% but hospitalizations and severe illness rose 15% and 29%, respectively. […] “We’ve so far identified the same 90% to 95% efficacy against the British strain […] It’s too early to say anything about the South African variant.” [Reuters]

The index case was a symptomatic patient in whom isolation was discontinued after 2 negative results on nasopharyngeal polymerase chain reaction testing. The patient subsequently infected multiple roommates and staff, who then infected others.

Susceptibility to infection such as SARS-CoV-2 may be influenced by host genotype. We found heritability of 49% (32−64%) for delirium; 34% (20−47%) for diarrhea; 31% (8−52%) for fatigue; 19% (0−38%) for anosmia; 46% (31−60%) for skipped meals and 31% (11−48%) for predicted COVID-19.

The idea was to provide medicines preventing or treating COVID-19 at a low cost or free of charge, the British university said. […] “We actually thought they were going to do that,” James Love, director of Knowledge Ecology International, a nonprofit that works to expand access to medical technology, said of Oxford’s pledge. […] A few weeks later, Oxford—urged on by the Bill & Melinda Gates Foundation —reversed course. It signed an exclusive vaccine deal with AstraZeneca that gave the pharmaceutical giant sole rights and no guarantee of low prices—with the less-publicized potential for Oxford to eventually make millions from the deal and win plenty of prestige.

Covid reinfections may be more common than realized. In Washington state, health officials are investigating nearly 700 cases that meet the criteria for possible reinfection. In Colorado, officials estimate that possible reinfections make up just 0.1 percent of positive coronavirus cases. In Minnesota, officials have investigated more than 150 cases of suspected reinfection.

During the second wave, in autumn 1918, cantonal authorities initially reacted hesitantly and delegated the responsibility to enact interventions to municipal authorities [..] A premature relaxation of restrictions on mass gatherings was associated with a resurgence of the epidemic. Strikingly similar patterns were found in the management of the COVID-19 outbreak in Switzerland.

Vitamin D supplementation to the older adult population in Germany has the cost-saving potential of preventing almost 30,000 cancer deaths per year

The rectal depth to which the thermistor is inserted affects measurement of rectal temperature. Clinicians should insert flexible rectal thermistors 15 cm (6 in) into the rectum.

McKinsey Settles for Nearly $600 Million Over Role in Opioid Crisis — The consulting firm has reached agreements with 49 states because of its sales advice to drugmakers, including Purdue Pharma, the manufacturer of OxyContin.

The Shocking Meltdown of Ample Hills — Brooklyn’s Hottest Ice Cream Company — They had $19 million, a deal with Disney, and dreams of becoming the next Ben & Jerry’s. Then everything fell apart.

Facing deficit (a potential shortfall of $150 million because of the pandemic), the Metropolitan Museum of Art has begun conversations with auction houses and its curators about selling some artworks to help pay for care of the collection. [NY Times]

People often use short timezone abbreviations like EST and PST to refer to timezones. If you’re doing this in a computer program, you are almost certainly making a huge mistake.

America’s Most Hated Office Jargon — Synergy, Teamwork, Thinking outside the box…

The Uni boxing Glove