Karma karma karma karma chameleon, you come and go, you come and go

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According to the U.S. Department of Agriculture, honey bees pollinate 80% of our flowering crops, and are thus essential for the production of 1/3 of our food. […] But for more than 2 million Americans, bees are a dangerous threat. Somewhere between 1% and 7% of human beings are allergic to insect venoms, with their symptoms ranging from mild overreactions to full-blown anaphylactic shock. For those with bee allergies, even the slightest sting can lead to a fight for life. Even more troubling is that, in half of all fatal sting allergy cases, victims had no previous major reactions to venom. Nearly 100 Americans die every year from bee stings. […]

Allergies are defined as ‘hypersensitive immune responses’—or, in colloquial terms, odd moments when our immune systems flip out. Anaphylaxis is the whole-body manifestation of an allergy, which can range from something as minor as hives to sharp drops in blood pressure and even cardiac arrest. You don’t have an allergic reaction the first time you come in contact with an allergen; instead, like with viruses or other potential invaders, your body takes an immunological picture so it can remember the allergen later. This is what is known as the adaptive immune response, and it’s usually a good thing—when you get the chicken pox, for example, your adaptive immune system remembers what the disease looks like, and can find and kill it should you ever be re-exposed. But when it comes to allergies, the adaptive immune system goes too far. The next time it detects allergens, it sends out hordes of IgE antibodies to destroy them. These IgE antibodies wreak havoc in our bodies—through cascading immunological pathways, IgE antibodies cause the release of histamine and other inflammatory compounds and can lead to anaphylaxis.

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